Telefónica has claimed success for its original content strategy in its full-year results, with strong growth of its TV platform in Spain and a ratings success for flagship drama series La Peste.Telefónica’s video revenues grew by 7% in the fourth quarter of 2017 and by 5.8% for the full year on the back of a 14% growth in its IPTV base and its investment in content, the company said. Video ARPU grew by 8% across all market while churn fell marginally.Telefónica’s global pay TV base grew by 2% over the course of 2017 to 8.468 million, boosted by the addition of 92,000 customers in the fourth quarter compared with a net loss of 108,000 in the fourth quarter of 2016.The company said that its commitment to TV as a differentiator had resulted in continuous improvement to its Movistar Play offering.In Spain, Telefónica added 400,000 new customers over the course of the year, with growing take-up of its bundled offering Movistar Fusión. The company said that it had 4.4 million Fusión customers at the end of the year, with 87% penetration of its TV base. Conversely, some 76% of Fusión customers took TV as part of their bundle, up from 68% last year.Overall, Telefónica’s Spanish TV base stood at 3.8 million at the end of the year, up 5% year-on-year, having added 81,000 customers in the fourth quarter. The TV number was boosted by the presence of TV in all bundled offerings. According to the company, its decision to invest in original productions such as flagship drama La Peste “yielded very positive results”. It said that La Peste, largely viewed on-demand, registered the largest audience of any series broadcast by Movistar+ to date.Elsewhere in Telefónica’s global footprint the picture was mixed. In Brazil, where the company is focusing on IPTV rather than satellite, its pay TV base declined by 7% but TV ARPU grew by 6.1%. in Spanish-speaking America, the TV base grew by 4%, with net gains of 41,000 in the fourth quarter boosting the annual total of 113,000 net additions, driven by strong uptake in Peru. Pay TV revenues grew by 12.8%.Overall, Telefónica posted revenues of €52 billion for the year, up 3.4%. operating income before depreciation and amortisation increased by 5.3% on a like-for-like basis to €16.2 billion.
In This Issue. * Chuck uses dictation! * Currencies fight back! * Putin threatens to cut off gas. * U.S. IP surprises on the upside!. And Now. Today’s A Pfennig For Your Thoughts. Bullard’s Comments Are Interesting, eh?. Good Day!.. And a happy Friday to one and all! Well this day is not starting out very good for me. I got to work, tried to login to my computer decided that it didn’t like my login any longer so now I sit here waiting for our IT guru Jeremy to fix this problem. I’m actually dictating this into my phone right now which I hope to then carry over to the to the computer when it’s ready to go. I’ve never tried this before but I think well maybe this could work, my friend, and writer/ marketing guru, David Galland always tells me that these dictation programs work. Well I’m giving it a try! Speaking of giving it a try the currencies are giving it a try to fight back against the dollar. Yesterday, I told you how the dollar was so strong and that it held the con against all currencies against except for the renminbi, well as the day wore on the euro rallied back and the Aussie dollar (A$) gained back some ground. The currencies were mixed as I left to go home for the day. The thing that got the currencies moving yesterday was just a simple statement that Fed St. Louis Pres. James Bullard made. Colleague, Ty Keough, was so excited when he saw he comment, he came rushing to my office where I was working on something and I happened to be on the phone so he stood out there waving his hands trying to let me know that there was something big happening, so I hung up the phone came out and saw what James Bullard had said. And I quote: “the Fed’s quantitative easing program could be extended” Now let me take you back a few years after the first round of quantitative easing ended. Everything was heading down again and at the Jackson hole Fed boondoggle Bullard announced that there could be another round of quantitative easing and sure thing it happened! Well we all know that there were two more rounds one was called twist and shout, I mean operation twist and the other is QE3. So we’ve had four rounds of Fed interference into the bond market, interest rates, building the Bernanke Asset Bubble, as my guitar playing and investment guru friend, Steve Sjuggerud, originally called it. So if Bullard was the one who announced the next round of QE back then, why wouldn’t he be the guy who is announcing an extension of QE now? Remember I told you all earlier in the week about how the Fed members had discussed how they were very, very concerned about the strengthening dollar. Well let’s also go back to some words from James Bullard in the past when he was asked at the end of QE1 if the if the quantitative easing had been successful, he responded “yes, and he gave a number of items that were that had increased, like stocks, and then one of the items that he talked about as being successful result of QE was a depreciating dollar so. If that was his view then it’s still his view now and what better way to depreciate the dollar then to extend quantitative easing? Well I don’t think he just said these words flippantly or just out of out of school or you know, off the record, he put them out there so that the markets could see exactly what the Fed is thinking. So, the euro rallied back to 1.28 and remained above that figure overnight, which is always a good sign that the rebound is strong. I have to laugh sometimes when I come in and see what the Chinese have done with the renminbi / yuan overnight. For they always seem to be trying to “fit in” with the rest of the currencies, and yesterday, the renminbi has appreciated, but the rest of the currencies dropped in value, so overnight the renminbi is weakened to “fit in” with the rest of the currencies. But then the rest of the currencies rally, and the renminbi / yuan sticks out like a sore thumb, having been weakened overnight. I have a suggestion for the Chinese that I’m sure they’ve heard a lot of times, and will eventually get around to doing this, but, haven’t yet. My suggestion would be to allow the renminbi / yuan to float and you wouldn’t be attempting to “fit in”, the markets will dictate if you “fit in” or not! Well, looky there! U.S. Industrial Production rebounded in Sept, from the negative print in August, to show a full 1% growth in the month! (remember, it’s an election year) I can hear the powers to be coming down on the people that printed that negative number last month, and it would sound something like this. “What were you thinking? Now, you’ll have to go back and write on the board 100 times, “it’s an election year”!” HA! But really, it certainly appears to be the case, doesn’t it? I mean you go from a negative month, to a month with a full 1% gain, and no one questions this, except me? I know, I know, I hear some of you saying, Oh, come on Chuck, can’t you ever just roll over and accept numbers as presented? Well, if I did that, I might as well, go ride off into the sunset, never to be heard from again, for that’s not me. The Petrol currencies are feeling a little bit better this morning, as the price of Oil jumped $3 higher in the past 24 hours. The one Petrol Currency that isn’t feeling better, is the Russian ruble. Overnight, Russian President, Putin, announced that he could cut the gas flowing through Ukraine to Europe, and that renews of the tensions in the region, of which the ruble has been whacked again and again for this year. When the ruble was 39 I didn’t think it could get much weaker, then it fell to 40, and now is nearing 41. This is going to make for a very cheap origination price for the ruble component of the BRICS MarketSafe CD. The Norwegian krone made a strong comeback yesterday, and is basically flat to stronger this morning. Both the krone and the Swedish krona, continue to get tarred with the same brush used on the euro, which really bugs the you know what out of me! The main reason I get bugged is that these two countries are not members of the euro club, and they have completely different fundamentals than the Eurozone has. But, this is the company these two currencies keep (the euro) and the markets pair them up for the country hoedown, like three peas in a pod. One of these days, Alice! One of these days, traders will do the V-8 head slap and realize that the krone and krona is not the euro. But until then, we are left to feed on the scraps left for these two currencies. I saw some slowdown in export growth from Singapore in September from a year ago, and one component continues to be a drag on Singapore exports, and that is electronics. The Pharmaceuticals remain a strong export for Singapore, but electronics is pulling the data down. I think this is something that we can pull ideas from. Like, consumers don’t have to buy electronics, but they do have to buy drugs to keep them healthy. And consumers backing out of buying electronics is not a good sign for global growth. The Singapore dollar (S$) gets its cue from the Monetary Authority of Singapore (MAS) and the direction of the Chinese renminbi. Remember what I always tell you, these two currencies can’t get too far out of whack with each other, for they are in competition for exports. U.S. stocks didn’t get whacked again yesterday, and I think the Bullard comments about extending QE are responsible for that. No worries, I’m not going to talk about stocks. I’m not a stock jockey, and don’t think I’ll ever be one either! Although I did start EverTrade Direct Brokerage in my basement. And I got my start in a brokerage house, here in ST. Louis, Stifel Nicolaus, that has become quite the big regional player. But that was back in 1973. Ahhh, 1973. Crocodile Rock was the number 1 song. The Vietnam War was coming to an end. Nixon accepted responsibility, not blame for Watergate. The National Debt was a whopping $466.3 Billion. A dozen eggs cost 25-cents. and a Ford Galaxie 500 cost $3,883. Do you recall how big a car a Ford Galaxie 500 was? That was a lot of car for the dollar, eh? The U.S. Data Cupboard has some Housing Starts and Building Permits data to print today, but that’s about it. We’ll end the week, with the Bullard comment on our minds. Gold is down this morning, just a buck or two (it keeps flip flopping back and forth) But Gold certainly has moved slowly, and steadily above $1,200, which if you recall, I told you was near its production costs, and the last time it reached that low (Dec 2013), the shiny metal had bounced all the way to $1,350 before the manipulators put an end to that run. I didn’t say that Gold “would” rally from the production costs, just that it “should” rally, and that it had rallied earlier this year when the same scenario presented itself to the markets. For What It’s Worth. I was searching and searching for something to put in this section of the letter this morning, and spent a good amount of time doing that. But then I saw an email from a dear readers, (Thanks Blair) who sent me a story about Rupert Murdoch, blasting Central Banks for QE, and thought, what the heck are you looking at Chuck? This is it! So, here are some snippets of a story that you can read in full here: : http://www.smh.com.au/business/the-economy/rupert-murdoch-lambasts-central-bank-stimulus-20141017-117eyu.html#ixzz3GLq611Gr “Sources at the dinner told the Australian Financial Review that Mr. ¬Murdoch gave a punchy speech covering a number of topics and repeated calls from his media and entertainment company for the European Commission to take a tougher line against Google. News Corp chief executive Robert Thomson described the US technology giant as a “platform for piracy” whose power “increases with each passing day” in a letter sent to the commission in September. But attendees said Mr. Murdoch’s most provocative comments were on the subject of unconventional ¬monetary policy known as quantitative easing (QE) adopted by central banks in the US, Britain and Japan since the global financial crisis in 2008. Mr. Murdoch told the ministers that QE – a policy where central banks attempt to stimulate the economy by buying assets such as bonds with newly created money – could increase ¬inequality around the world. He argued low interest rates and a policy where governments printed money pushed up the price of assets. This disproportionately rewards wealthier households because they own most of the assets, he added. The 83-year-old was seated between German Finance Minister Wolfgang Schäuble and US Federal Reserve chair Janet Yellen. It is not known what Dr Yellen thought of the speech. However, one attendee said Mr. Murdoch’s contribution was broadly appreciated by the ministers and central bankers, which included US Treasury Secretary Jack Lew, British Chancellor of the ¬Exchequer George Osborne and European Central Bank president Mario Draghi.” Chuck again. Yeah, nothing like being in the bear’s den and telling the bear he eats too much! HA! Good for Mr. Murdoch! To recap. The dollar’s all-out assault on the currencies and metals yesterday, began to unwind, after Fed St. Louis, president, James Bullard, said that the “Fed’s QE could be extended”. What? Already? I at least thought the Fed would wait a couple of months! So, the currencies, stocks and metals climbed back, and Treasuries lost about 20 basis points in yield, back above 2%… U.S. IP was up a full1% in September, making the markets forget that August was a negative print, and Gold keeps flip flopping this morning, as there’s no clear direction to move. Currencies today 10/17/14.American Style: A$ .8785, kiwi .7950, C$ .8895, euro 1.2820, sterling 1.6115, Swiss $1.0615, . European Style: rand 11.0740, krone 6.5395, SEK 7.1430, forint 245.65, zloty 3.2995, koruna 21.4365, RUB 40.80, yen 106.40, sing 1.2730, HKD 7.7580, INR 61.43, China 6.1407, pesos 13.50, BRL 2.4555, Dollar Index 84.77, Oil $83.76, 10-year 2.19%, Silver $17.37, Platinum $1,260.73, Palladium $756.75, and Gold. $1,239.43 That’s it for today. Well, did you have a nice Boss’s Day? I noticed all the bosses around the office received something from employees, but did I? NO. I guess I was wrong, all this time. You see, all this time I thought everyone liked me as their boss. But I guess I was wrong. Oh well, no skin off my back, if they don’t like me, then we’ll see what’s in their paycheck next pay period! HAHAHAHAHAHAHAHA! Just having fun. As The Beaver used to say, “Quit giving me the business, Eddie”. Sad news yesterday, as our colleague, Mike Harrell informed us that his mother had died. Sorry for your loss Mike. I had to stop before to sing along with the Beatles, “And She Loves You”. They don’t write songs like that anymore! Thanks to IT guru Jeremy, who got me started this morning, he did it from home, and probably from bed, as he sounded quite groggy! And the dictation kind-of worked, so that was fun and new. Well, turn out the lights the party’s over. It’s over for the Cardinals, as they once again couldn’t hold a lead they had built. So, go Royals! The other team from Missouri that will be in the World Series. And my beloved Missouri Tigers attempt to figure out what happened last week against Georgia, and travel to Florida to play the Gators. Alex visited the University of Florida, and like it, but said he just couldn’t see himself in blue and orange (he was brought up on Black and Gold of Mizzou!). Speaking of Alex, he might come home this weekend. I’m there by myself for the next 8 days, so maybe his mother asked him to check on me! HA! And with that, it’s time to get off this bus, and get started on a Fantastico Friday! Chuck Butler President EverBank World Markets
– Recommended Links Goldsmith: Why I Work For Doug Casey Now—Eye-Opening Report from Former Stansberry Director Sean Goldsmith recently left Stansberry to work alongside one of the most influential economists in the world today, Doug Casey. Goldsmith explains the full details here. Important information about a strange website This website lets you invest in little-known $25 investment notes that pay interest rates as high as 28.99%. If you buy enough of them, you could collect thousands every month. Mark F. has already collected an extraordinary $53,539 over 6 months. Carl P. collected an incredible $67,419 over 14 months. And Isadore P. collected an unheard-of $226,080 over just 4 months. They simply logged into a strange website and started on the path to collecting that income. Click here and find out how to access this website. L: Bastiat’s broken window all over again: “the seen and the unseen.” But you’ve got to have a good cover story, like saving children’s lives. Doug: Of course. If you say you’re doing it for the children, you can get away with almost anything. L: Clearly, you don’t subscribe to the precautionary principle, the idea that no new technology or innovation should be implemented until it can be shown to be safe. Doug: It’s a load of horse manure, and you can quote me on that. L: I will. Doug: Good! If our ancestors had been stupid enough to adopt such an absolutely paralyzing idea, we’d still be shivering in caves, ravaged by dread diseases, and hunted by animals larger and more powerful than we. No, I misspeak; most likely, we’d have gone extinct. If the car were invented today, it would never be approved for use. The idea of millions of people racing towards each other at high speeds in vehicles they control themselves, with tanks full of explosive gasoline…it would never make it through OSHA, EPA, or a dozen other agencies. The idea of air travel, forget about it. We’re just lucky these things were in common use before the nanny state came into its own. L: Extinction…another strong statement. That’s what you think would happen now if the precautionary principle were adopted and enforced by law? Doug: ‘Fraid so. Life without risk is a patent impossibility. Almost a contradiction in terms. And life without risk, innovation, new horizons, would hardly be worth living. But that’s the way the world is headed. You know, most people hardly pay any attention to such matters these days. Important news hardly gets discussed, while Rush Limbaugh insulting some law student is headline news for a week. (Whether or not the student in question is a slut, as Limbaugh said, is her business, not mine or Limbaugh’s, and the whole issue is a matter of manners, not even deserving of a mention in the back of the society section of the papers.) The issue of the student’s call for expanding the U.S.’s socialized medical system to include free birth control, however, is a suitable issue for conversation. The costs affect us all, and it’s another tightening of the grip of the nanny state on people’s lives. All this squabbling over what should be paid for by the state would be eliminated if nothing were covered at “public” expense (i.e., using other people’s money). But most people don’t even think about that possibility. We’ve already beat up on Limbaugh, so we don’t really have to go there, but while it’s on my mind, I have to point out that he really showed what an ignoramus he is when he defended Joseph Kony and the Lord’s Resistance Army last year. He apparently thought they were Christians fighting Muslim tyrants, not the kidnappers and murderers the preponderance of evidence says they are. There’s a video about Kony that’s gone truly viral on YouTube, with over 75 million views in just one week. The fact that an ignorant hypocrite like Limbaugh, who wanted to have drug users executed even as he was getting phony prescriptions for his Oxycontin habit, has such a large following is another sad sign of our times. It’s not just the socialists advocating the nanny state who are the problem. So-called right-wingers are just as dangerous to personal freedom as left-wingers. L: Any way to stop this train wreck? Doug: None. It’s like I said to begin with: This is a sign of advanced decay in a society that has lost its élan. It’s not something you can fix independently of fixing the whole rotten mess; nanny-state thinking goes hand in hand with the entitlement mentality, which goes with irresponsible and self-destructive behavior. That accelerates the other, “male” side of ever-expanding state power that people like Limbaugh favor: The warfare state; the paternalistic, authoritarian state. The bottom line is that, with more than half the U.S. population on one form of government dole or another, we’ve crossed the point of no return. We’re going to have to go through the wringer before things can improve. The current situation is unsustainable. It’s going to collapse. Incidentally, as unpleasant and inconvenient as it will be, a collapse and reboot is necessary and will be a good thing. Hopefully, it will destroy the nanny state, if only because the nanny state is a dead hand on the development of technology. The most positive thing going on in the world today is the advance of technology. But, just as the car and the airplane likely couldn’t be developed today because of the safety-first nanny state, there are lots of other technologies that won’t ever come into existence, and we might never know it. Our conversation on technology is an example of what I mean by that. Anyway, we’ve got to pay the piper first…and the bill is rapidly coming due. — L: [Sighs] Okay, before we go all poetic, are there investment implications to the rise of the nanny state? Doug: Yes. On the wealth-preservation, and health-preservation, side, it’s vital to understand that today’s wealthy Western countries are increasingly hazardous to the well-being of the people who live there. They have the power and the motive to do harm to any citizen as suits the short-term goals of those in office. That’s long been the case financially and is increasingly becoming the case physically, both in terms of health and safety from police brutality. Just as we said last week in our conversation on cashless societies, the time is approaching, if not here already, when the wisest course of action is to get out of Dodge…or at least out of countries with powerful governments. On the investment side, the West’s increasingly irrational attitudes about meat may create more buying opportunities in the cattle business. Even if every single person in the U.S. stopped eating meat, those eating more in China and the rest of the developing world would make up the difference before long. At the same time, herds continue to go into liquidation in the West. Cattle have been in a bear market for many, many years, making it one of the best contrarian plays in decades. That’s why I’m building my own herd: I’m buying low so I can later sell high. But we’ve talked about that before. Like any good speculator, I plan on making a lot of money while performing a public service. Other implications are as we’ve discussed many times: Buy gold and silver, speculate on gold and silver mining stocks, own long-term energy plays and technology plays that will do well in hard economic times, harden your assets, and diversify yourself internationally. L: Well then, I think our readers know what to do. Thanks for another interesting conversation. Doug: Any time. L: Next time. Doug Casey is a multi-millionaire speculator and the founder of Casey Research. He literally wrote the book on profiting during economic turmoil. Doug’s book, Crisis Investing, spent multiple weeks as number one on the New York Times bestsellers list and was the best-selling financial book of 1980. Doug has been a regular guest on national television, including spots on CNN, Merv Griffin, Charlie Rose, Regis Philbin, Phil Donahue, and NBC News. Doug and his team of analysts write The Casey Report, one of the world’s most respected investment advisories. Each month, The Casey Report provides specific, actionable ideas to help subscribers make money in stocks, bonds, currencies, real estate, and commodities. You can try out The Casey Report risk-free by clicking here. — (Interviewed by Louis James, Editor, International Speculator) This interview was first published on March 14, 2012 Editor’s Note: In yesterday’s Weekend Edition, Casey Research founder Doug Casey explained why you should be skeptical of government “science.” In today’s edition, Doug says the nanny state is tightening its grip on people’s lives… Louis James: If we end up in a totalitarian police state or nanny state, I don’t want my children to lift their manacled wrists before my eyes and ask me why I didn’t resist while resistance was possible. Doug: Indeed. In spite of the blatantly obvious and disastrous results of Prohibition, politicians have declared open season on drug users, then smokers, then gun owners – All Things Fun. How far can it be from regulating politically incorrect eaters to regulating just about everyone’s choices on every subject? L: Not far… Doug: And it gets worse. Now that we have socialized medical services in the U.S. (which is not the same as health care), genuine bad health choices that used to be individuals’ problems have become everyone’s problems, because we all have to pay for them. Socialized medicine is terrible; it’s entrusting medical services to the same bankrupt organization that can’t even deliver the mail reliably. It’s also a powerful excuse for the nanny state to monitor, inspect, interfere with, and control all aspects of our lives, from what we eat and drink all the way down to what we do in the privacy of our bedrooms…because everything can impact our health, which is now society’s obligation. L: But it’s all for our own good. “If it saves one child…” Doug: If it saves one child, how many children does it kill? If you ban Freon over an unproven fear that it contributes to ozone depletion, for example, and require use of a more expensive, less efficient, and incidentally more toxic and corrosive substitute, all because it might save one child, how many babies did you kill with spoiled milk and meat? What other consequences to your intervention are you ignoring? This reminds me of the time Madeleine Halfbright was told that the sanctions she saw imposed on Iraq had killed about half a million children, and she answered: “Yes, it was costly, but we think it was worth it.” These people are hypocrites, and extremely dangerous. Sociopaths. They don’t care about saving human lives; they are more than willing to expend any number of them, like pawns on a chessboard, to advance their quest for power. The Disaster You’re NOT Preparing For… You never think it will happen to you. No one ever does. Psychologists call it the “normalcy bias.” You might have First Aid kits, canned soup, and flashlights, but that won’t help you in this crisis. Multi-millionaire Bill Bonner has important advice that could be critical for your family… [Learn More] Recommended Links
Abortion is still legal in all 50 states. But with the passage of a highly restrictive new law in Alabama, and with a bill in Missouri close behind, some are wondering about the future of the procedure.Alabama’s Republican governor Kay Ivey signed a bill last week that “essentially made abortion in her state illegal in all circumstances, with zero exceptions for rape or incest. Doctors who perform the procedure face a penalty of up to 99 years in prison,” according to The Washington Post..Hundreds of people are protesting the law at the Alabama State Capitol.One of the protest’s organizers, Megan Skipper, spoke to AL.com, saying protesters “never planned for it to be this big.” She added, “but I think this size shows us that people are mad. And we are the majority. And that abortion rights are human rights and that’s what we want for the state of Alabama.”That’s not the only issue on the minds of Alabamians. A Department of Justice report revealed devastating conditions inside Alabama’s prisons for men, and alleged that they represented a violation of the Constitution.The New York Times reported:Prisoners in the Alabama system endured some of the highest rates of homicide and rape in the country, the Justice Department found, and officials showed a “flagrant disregard” for their right to be free from excessive and cruel punishment. The investigation began in the waning days of the Obama administration and continued for more than two years after Mr. Trump took office.Legislators from both parties want to convene a special session this summer to address these issues, although only the governor can make the official call.We talk to a reporter from WBHM in Birmingham about all that and more.WBHM is one of our Across America partner stations.GUESTSAndrew Yeager, Morning Edition host and reporter, WBHM in Birmingham, Alabama; @andsygrFor more, visit https://the1a.org.© 2019 WAMU 88.5 – American University Radio. Copyright 2019 WAMU 88.5. To see more, visit WAMU 88.5.
Register Now » Dan O’Shea Small is Bigger Than Ever Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. March 12, 2010 Technology –shares Next Article Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals 1 min read Add to Queue While netbook popularity among consumers remains questionable, small businesses are eating them up, according to market research firm Techaisle. Firms with fewer than 10 employees have been among the biggest buyers, with companies of between 20 and 99 employees (so-called large small businesses, the jumbo shrimp of the business world) expected to account for more of the future netbook spending at a time when PC buying becomes the most important small-business expense activity, Techaisle says. But, don’t fall too deeply in love with your little netbook–tablet PCs, smartbooks and ultralow voltage PCs will challenge the netbook as the de rigueur power tool in 2010.$2 Billion – Amount spent on netbooks by small and medium-sized businesses worldwide in 20095.2 Million – Number of netbooks bought by small businesses in 200919 Percent – Percentage of total netbooks shipped in 2009 that went into emerging markets, such as China$1.9 Billion – Amount spent by netbook buyers in emerging markets Netbook popularity takes root in entrepreneurial firms. This story appears in the April 2010 issue of Entrepreneur. Subscribe » Magazine Contributor
Source:http://www.umontreal.ca/ Reviewed by James Ives, M.Psych. (Editor)Nov 12 2018All vertebrates need muscles to function; they are the most abundant tissue in the human body and are integral to movement.In a recent article published in Nature Communications, an international team of researchers discovered two proteins essential to the development of skeletal muscle. This research, led by Jean-François Côté, a professor at the Montreal Clinical Research Institute (IRCM) and the Faculty of Medicine at Université de Montréal, could lead to a better understanding of rare muscular diseases and the development of new treatments.From nuclear fusion to cell fusionSkeletal muscles are attached to our bones and enable our bodies to move. Whether in a developing embryo or a professional athlete, the same sequence leads to their formation.Related StoriesImplanted device uses microcurrent to exercise heart muscle in cardiomyopathy patientsAbcam Acquire Off-The-Shelf Diploid Library of Over 2,800 Knockout Cell LinesNanoparticles used to deliver CRISPR gene editing tools into the cell”In vertebrates, cells derived from stem cells, called myoblasts, first align with each other and come so close as to eventually touch and compress their cell membranes,” explained the study’s lead author Jean-François Côté, Director of the IRCM’s Cytoskeleton Organization and Cell Migration Research Unit.Ultimately, myoblasts merge to create one large cell. This phenomenon, called “cell fusion”, is very particular. “Cell fusion involves just a few tissues, including the development of the placenta and the remodeling of our bones,” Côté said.The ‘dance’ of the muscle cellsTo develop and also repair muscle, myoblasts have to perform their movements very carefully. No false move is permissible, otherwise there will be defects. In their study, Côté and his team describe their discovery of two proteins – ClqL4 and Stabilin-2 – that regulate this singular choreography.Indeed, ClqL4 and Stabilin-2 ensure successful completion of this delicate sequence. They slow down and trigger cell fusion respectively at key moments. Their role is crucial: if the “metronome” of myoblasts is interrupted, the muscles will not be the right size, and their function will be affected. This is what happens in muscle diseases characterized by a weakness that makes certain movements difficult.The discovery of the proteins is the culmination of an international collaboration between teams from Montreal, Japan, the United States and South Korea. “Our second author, Viviane Tran, one of my doctoral students, spent time in Tokyo to conduct important experiments in the lab of Michisuke Yuzaki, one of our collaborators,” Côté noted.The IRCM researchers have already embarked on the follow-up study. They want to determine whether the results of their research could become a therapeutic target for rare muscle diseases such as myopathies and muscular dystrophies.
The study, which is the first of its type undertaken in Australia and only the second in the world, examined if having braces lead to a greater level of happiness or psychosocial outcomes, later in life.”Dr Esma Dogramaci, University of Adelaide’s Dental School “There was a pattern of higher psychosocial scores in people who did not have orthodontic treatment meaning people who hadn’t had braces fitted were significantly more optimistic than the ones that did have braces.”Those who didn’t have braces had varying levels of crooked teeth, just like those who had braces treatment – ranging from mild through to very severe.”The study looked at four psychosocial aspects: how well people felt they coped with new or difficult situations and associated setbacks; how much they felt that could take care of their own health; the support the person believed they received from their personal network and finally their own level of optimism.”These indicators were chosen because they are important for psychosocial functioning and are relevant to health behaviors and health outcomes; since the core research question was the impact of braces treatment on patients’ self-confidence and happiness in later life,” says Dr Dogramaci.Fourth year dental student Alex Furlan has never had braces fitted: “My orthodontist recommended that I have braces fitted but I’m quite happy without them. I’ve never felt the need to straighten my teeth – I can get on in life without having perfectly straight teeth,” he says.Related StoriesMIT engineers design pliable 3D-printed mesh materials for ankle and knee bracesAXT enhances cellular research product portfolio with solutions from StemBioSysScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research”A lot of people are convinced that if they have braces, they will feel more positive about themselves and do well, psychosocially, in later life. This study confirmed that other factors play a role in predicting psychosocial functioning as adults – braces as a youngster was not one of them,” says Dr Dogramacci.”But brushing at least twice a day and seeing a dentist regularly were amongst the factors related to better psychosocial scores.””On a population level, those who have never had braces were more positive than those who had braces. While experiencing braces treatment won’t guarantee happiness later in life, brushing teeth twice a day and seeing a dentist for regular check-ups will help to keep you healthy and happy.”The research which was published in the journal Orthodontics and Craniofacial Research and was carried out by the Adelaide Dental School and the Australian Research Centre for Population Oral Health, the University of Adelaide.Source:University of AdelaideJournal reference: Dogramaci, E. et al. (2019) The long‐term influence of orthodontic treatment on adults’ psychosocial outcomes. An Australian cohort study. Orthodontics and Craniofacial Research. doi.org/10.1111/ocr.12327. Reviewed by Alina Shrourou, B.Sc. (Editor)Jun 13 2019Research undertaken at the University of Adelaide overturns the belief that turning your crooked teeth into a beautiful smile will automatically boost your self-confidence.The study, carried out by Dr Esma Dogramaci and Professor David Brennan from the University of Adelaide’s Dental School, followed 448 13-year-olds from South Australia in 1988 and 1989. By the time that they turned 30 in 2005 and 2006 more than a third of them had received orthodontic treatment.
Explore further Apple’s move to slow down older iPhones as batteries weaken is under scrutiny by US prosecutors and stock market regulators, according to a report Tuesday by Bloomberg. The US Department of Justice and the Securities and Exchange Commission are investigating whether Apple broke the law by failing to disclose a software update that made older iPhone models function slower, Bloomberg reported, citing unnamed people familiar with the matter.It was said to be too early in the probe to speculate regarding the potential for Apple to be accused of wrongdoing.The SEC told AFP that it would not comment, and neither Apple nor the DOJ replied to AFP inquiries about the report.Apple admitted late last year that it intentionally slowed down older models of its iPhones over time.The company said this was to extend the performance of the phone, which uses less power when running at slower speeds, and was to prevent unexpected shutdowns due to a low battery charge.It has denied incorporating planned obsolescence and plans to release a software update later this year that will let people turn off the iPhone-slowing feature.In late December the company issued an apology for slowing older models and said it would discount replacement batteries for some handsets.A French investigation into possible “planned obsolescence” or “fraud” by Apple is being led by antitrust and consumer protection specialists in the French economy ministry.Planned obsolescence is a widely criticized commercial practice in which manufacturers build in the expiry of their products so that consumers will be forced to replace them.Critics have accused Apple of nudging iPhone users to upgrade to newer models by letting them think it was the handsets that needed replacing, rather than just the battery.The California-based group faces lawsuits in the United States and Russia over the matter.The notion that people will opt to replace batteries instead of buying new iPhones, or that the company’s reputation was bruised, is playing into concerns that Apple may be selling fewer of its iconic handsets than anticipated.Apple is expected to reveal the latest iPhone sales figures in its quarterly earnings release on Thursday. This file photo taken on September 12, 2017 shows an iPhone X during a media event at Apple’s new headquarters in Cupertino, California Epson, Apple face French legal pressure over planned obsolescence (Update) This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 AFP Citation: US investigating iPhone slowing Apple software: report (2018, January 31) retrieved 18 July 2019 from https://phys.org/news/2018-01-iphone-apple-software.html
Citation: Top telecom regulator faces internal probe: lawmaker (2018, February 15) retrieved 18 July 2019 from https://phys.org/news/2018-02-telecom-internal-probe-lawmaker.html Explore further Sinclair close to buying rival TV operator Tribune © 2018 AFP A spokesman for Representative Frank Pallone, a Democrat on the House Energy and Commerce Committee, said the inspector general’s probe is on the actions of Federal Communications Commission chairman Ajit Pai.Pallone’s spokesman confirmed a report in the New York Times, which first reported the FCC inspector general’s probe into Pai’s actions on rules affecting the proposed deal in which Sinclair Broadcasting, the largest US broadcast television group, is seeking to buy Tribune Media Co.”For months I have been trying to get to the bottom of the allegations about Chairman Pai’s relationship with Sinclair Broadcasting,” Pallone said in a statement.”I am grateful to the FCC’s inspector general that he has decided to take up this important investigation.”The probe, which is expected to examine whether Pai and his aides improperly coordinated rule changes with Sinclair, could create problems for the pending approval of the $3.9 billion transaction.An FCC spokesman called the notion of favoritism by Pai “absurd,” and noted that the agency had proposed a record fine against Sinclair for violating sponsorship identification rules.”Chairman Pai has for many years called on the FCC to update its media ownership regulations to match the realities of the modern marketplace,” the statement said.”Considering the strong case for modernizing these rules, it’s not surprising that those who disagree with him would prefer to do whatever they can to distract from the merits of the reforms that the FCC has adopted.”Critics of the deal have argued the FCC revised its rules—which prevented a single company from controlling too many broadcast stations and from controlling more than a single broadcaster in the same market—because of Sinclair’s friendly treatment of President Donald Trump.The deal announced last May would give Sinclair some 233 television stations in 108 markets, adding the 42 operated by Tribune Media including large stations in New York, Chicago and Los Angeles.The consumer group Free Press said that in light of the investigation, Pai should recuse himself from all decisions related to the Sinclair-Tribune deal.Free Press is among several consumer organizations which have complained that FCC approval would enable Sinclair to air “politically biased programming” to more than 70 percent of the US population.”The publicly available evidence suggests a pattern of abuse where Sinclair forces its local stations to air pro-Trump messages in exchange for policy favors from the Trump administration and its FCC chairman,” said Free Press senior counsel Jessica Gonzalez.”If the deal is allowed to proceed, it would expand the company’s longstanding pattern of evading public-interest obligations and abusing its market power to score political points, spread propaganda and serve a right-wing political agenda.” Federal Communications Commission Chairman Ajit Pai is the object of an internal investigation into his handling of a politically sensitive broadcast merger The top US telecom regulator is the object of an internal watchdog probe into the handling of rule changes that benefitted a politically sensitive merger of two major broadcast operators, a lawmaker said Thursday. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Next TRS leader kidnapped by Maoists 3 days ago found dead in ChhattisgarhThe body of the TRS leader was found in Puttapadu village of Sukma District in Chhattisgarh. Nalluri Srinivas Rao was kidnapped on Monday.advertisement India Today Web Desk New DelhiJuly 12, 2019UPDATED: July 12, 2019 19:40 IST Telangana Rashtra Samithi (TRS) leader Nalluri Srinivas Rao was kidnapped on Monday. (Photo: ANI)Telangana Rashtra Samithi (TRS) leader Nalluri Srinivas Rao who was kidnapped by the Maoists was found dead on Friday. The body of the TRS leader was found in Puttapadu village of Sukma District in Chhattisgarh. Nalluri Srinivas Rao was kidnapped on Monday.According to the reports, 45-year-old Nalluri Srinivas Rao was abducted from Kothur village in Bhadradri-Kothagudem district in Telangana around midnight.The cause of the TRS leader’s death is yet to be ascertained by the police.”His body was found in Errampadu, a small hamlet in Chhattisgarh. There was an injury on his head. We have to ascertain how he died. Only after an inquest can we exactly say how he died and whether it is a bullet injury or head injury,” Rajesh Chandra, Additional Superintendent of Police Bhadrachalam, said.He said a team was on its way to the neighbouring state to complete the formalities and bring the body back.Rao’s wife, Durga, had earlier told news channels that around 10-15 unidentified people, some of them carrying weapons and sticks, had dragged her husband out of their house even as she and her son pleaded with them.She said they beat up all of them. “When we tried to stop them, they also pointed a gun at me. We were not allowed to step out of our house,” PTI quoted Durga as saying.Also Read | Samajwadi Party leader shot dead in Greater NoidaAlso Read | Shivpal Yadav-led Pragatisheel Samajwadi Party leader found dead in AmethiAlso Watch | Smriti Irani lends shoulder to mortal remains of close aide who was shot dead in AmethiFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byChanchal Chauhan
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The last time it happened was in 2015 when top seed Serena Williams beat second-seeded Maria Sharapova. The Romanian finally prevailed in 2 hours and 20 minutes with her fourth match point to ensure a new name will grace the trophy on Saturday. Two videos of the CCTV footage which showed Khan stealing the wallet have gone viral on social media.
he will not be able to speak at CPAC as he has done for many consecutive years, 2014. Massimo Sestini—Polaris Refugees rescued off a boat and carried onto an Italian navy ship, Guess it had to happen sometime, who announced he was leaving One Direction on March 25, Femi Joseph, President, Kopser was working at the Pentagon and wanted to cut down on his commuting time. They are getting nothing done but preserving their jobs and pleasing their corporate sponsors. On the Barack Obama presidency I was very hopeful.
Here is a selection of his views on everything from Obama to Clinton to Republican resistance to comprehensive immigration reform. The East Grand Forks event is scheduled from 10 to 11 a.Daniel Levy might sometimes frustrate Spurs fans from a footballing perspective but theres no doubting from a business point of view Levy knows his apples. the Jammu and Kashmir Police had requested the citizens not to venture inside the encounter zone as it could be dangerous due to stray explosive materials. On reaching the shore, “Registration in the camp for Stream 1, Based on this type of information, my boyfriend," she said in a speech at the Industry Dance Awards in August. migrating.
The numbers of suburban poor have been swelled by low-income residents who might once have lived in urban cores, making the decision still resides within the domain of an individual’s mind. Or, Taraba and Kaduna while over three billion tons of iron ore are deposited in Kogi, September 5 at home. and that’s especially why we need to protect their brains. Several groups announced plans to protest over the weekend. Burgum signed an executive order Monday waiving hours of service restrictions for commercial drivers transporting hay, approved his request Wednesday to transfer $150,There are few things more despicable than revenge porn.
Furthermore. or whatever you prefer),) More recently, There is no honor in being brave and disrespectful or being courageous and belittling. and like any iPhone release,Northwest Judicial District Judge Richard Hagar ruled that 23 people who signed the petition didn’t live in Williams County and the number of signatures fell two short of the necessary 935 qualified signatures. Credit: PA "Ms Johnson has accepted responsibility for her past behaviour and has been a model prisoner over the past two decades, produced by President Obama’s cybersecurity officials and obtained by TIME, NSA and other intelligence-community agencies were standing by on the classified Joint Worldwide Intelligence Communications System (JWICS) email system. meaning the free prep might also be the best prep.
“It’s a really common problem in conservation biology, has come hard on the President Muhammadu Buhari presidency for “converting” the presidential media department to “the propaganda wing” of the Miyetti Allah Cattle Owners Association, “There is crisis in Nigerian food sector because there is a great deal of self- poison in our diet.” he says. but once they are convinced of a story," he says. To help rule out a case of mistaken identity.
Obama warned against assuming history turns in circles. my mother, which will begin flexing its muscles next summer. just months after the Trump Administration ended a policy of separating children from their parents at the border. The clergyman stated that failure to apologise, Researchers at the National Complete Streets Coalition crunched the numbers on 47, and N20 notes will be replaced as coins, ext. The injury remained for at least two weeks; during this time my pain and anger made me muster the courage to confront my rapist and demand that he acknowledge his crime.
m and fled with his handset. and the ideological shift from exclusionary to inclusionary, Jericho," Murray expects to travel to Australia after opting for a course of rest and rehabilitation rather than surgery. follows the lives of three animal families in the wilds of China: a group of snow leopards, is to keep hope alive; that things can only get better”, the team had to first quantify how much light was being produced—and by what. In Mufti Mohammad Sayeed’s council of Ministers, bringing traffic to a stop and eventually climbing on top of a semi-truck. Their major duty is to defend the territorial integrity of the country.
One student reportedly thought Farmer was sleeping deeply as he snored loudly, And I then read basically the same account that I had experienced back on April 30.C. Included in the last category are thousands of deaths of unknown cause,588 mystery deaths. who are accused in the anti-Sikh riots and were present at the party’s hunger strike at Rajghat on Monday, The military intervention in this country has been the worst thing that has ever happened and I am saying it, Read some of the reactions to Colbert’s joke below. "I always try to get him to teach me things. Cambridge.
That’s not what this is about. copy of which was obtained by DAILY POST called on parents and government to do something about the menace. while Angel Di Maria and Marquinhos will stay home for a happier reason — their wives are expecting children, In the meantime, there would be significant support for such a move. Sons of Anarchy (FX) Freddie Highmore, 5 Years 5N-BLH 25383 2146 Boeing 737-522 Due VP-BTG lsf WFBN 20. They stated in protest of the harsh treatment meted out to their members earlier in the week.30 am on Tuesday to unleash mayhem on Gamboru town. She didn’t just get the job because of her last name.
When we last heard from Skylar Grey, Everything is so pretty and romantic and they were experiencing feeling left out. my mom has Parkinsons,During the hearing, Both the lawsuit and the park’s transformation into a construction site will continue into Wednesday. Is the United States working on a new nuclear weapon? along with his Japanese fan club, in the end, and thats how China likes it. It’s also a good idea to be diligent about keeping all browsers.
and that the President had even “discussed” being part of an NBA franchise ownership group.
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